If you have not eaten for about 3 hours, your body senses that it is going into starvation mode, reducing the metabolism rate, while increasing the production of fat-depositing enzymes. The means that you will not be burning as many calories as is normal, that you won't be as mentally or physically alert, and that more of your next meal will be stored away as fat.
If the starvation reflex starts working after 3 hours, then you can beat it by eating every 2 hours. This is a great way to burn more calories. A person who now eats 2-3 times a day can burn about 8-10 pounds a year more when he or she shifts to eating 8-10 times a day. This assumes that the same number of calories are eaten every day.